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The hidden functional diversity of macrophages
Our work identifies previously unrecognized functional heterogeneity in tissue-resident interstitial macrophages. We have identified ten macrophage subsets, each thought to specifically contribute to recruiting and organizing cell types within tissues. Moreover, our findings suggest the diversity and division of labor extend to other macrophage populations previously considered homogeneous.
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Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease
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Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice
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Predictability of B cell clonal persistence and immunosurveillance in breast cancer
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Coordinated chemokine expression defines macrophage subsets across tissues